Anti-UH-RA antibody reactivity for prediction of response to first-line therapy in rheumatoid arthritis: validation in the independent CAP48 cohort
Ondersteund project van Patrick Van Dormael : Recently, baseline antibodies against 3 University Hasselt (UH)-RA antigens were found to be predictive for failure to achieve response to first-line therapies in rheumatoid arthritis (RA) patients. In the current study, we will use the independent Belgian CAP48 patient cohort to validate the correlation between baseline antibody reactivity to UH-RA antigens and lack of therapy response, to determine additional antibody isotypes, and to study the variation in antibody levels during follow-up.
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KU Leuven (RA Clinical Research Group, Skeletal Biology and Engineering Research Centre, Department of Development and Regeneration, KU Leuven)
What is the optimal tapering strategy for rituximab in patients with Rheumatoid Arthritis: comparison of interval prolongation with disease activity guided dose reduction
Ondersteund project van Patrick Verschueren : Rituximab is an effective drug, but it is expensive and might be accompanied by an increased infection risk. Therefore, lowering the…
The prevalence of spondyloarthritis-like structural lesions of the sacroiliac joints on MRI in postpartum women.
Ondersteund project of Filip Van den Bosch : A former study in 35 healthy postpartum women showed prevalence of sacroiliac bone marrow edema (BME) on magnetic resonance (MRI), re…
Université Catholique de Louvain
Transcriptome study of individual cells isolated from synovial biopsies: can it help in the therapeutic management of early rheumatoid arthritis ?
Ondersteund project van Patrick Durez : Early diagnosis and therapeutic management of Rheumatoid arthritis (RA) are crucial. Early RA is treated with methotrexate (MTX) and after…