Anti-UH-RA antibody reactivity for prediction of response to first-line therapy in rheumatoid arthritis: validation in the independent CAP48 cohort
Supported project of Patrick Van Dormael : Recently, baseline antibodies against 3 University Hasselt (UH)-RA antigens were found to be predictive for failure to achieve response to first-line therapies in rheumatoid arthritis (RA) patients. In the current study, we will use the independent Belgian CAP48 patient cohort to validate the correlation between baseline antibody reactivity to UH-RA antigens and lack of therapy response, to determine additional antibody isotypes, and to study the variation in antibody levels during follow-up.
Have also benefited from support
KU Leuven (RA Clinical Research Group, Skeletal Biology and Engineering Research Centre, Department of Development and Regeneration, KU Leuven)
What is the optimal tapering strategy for rituximab in patients with Rheumatoid Arthritis: comparison of interval prolongation with disease activity guided dose reduction
Supported project of Patrick Verschueren : Rituximab is an effective drug, but it is expensive and might be accompanied by an increased infection risk. Therefore, lowering the do…
Université Catholique de Louvain
Transcriptome study of individual cells isolated from synovial biopsies: can it help in the therapeutic management of early rheumatoid arthritis ?
Supported project of Patrick Durez : Early diagnosis and therapeutic management of Rheumatoid arthritis (RA) are crucial. Early RA is treated with methotrexate (MTX) and after 3 …
UZ Leuven/ KU Leuven
Clinical field tests as predictors of cardiorespiratory fitness and cardiometabolic risk in Psoriatic Arthritis.
Supported project of Barbara Neerinckx : This project will study the potential of low cost, objective and highly generalisable clinical field tests, six minute walk and hand grip…