Université Libre de Bruxelles
Rescuing mutant CFTR by delivering stabilizing nanobodies
2023
Elsene
Project van Cédric Govaerts ondersteund door het Fonds A & J Forton en muco.be: 'We have developed stabilizing CFTR-nanobodies that can help rescue expression and function of mutant CFTR in synergy with currently approved correctors. They thus offer a route for improving current drugs or potentially treat mutations that are not eligible to these correctors. Our project aims at formulating nanobodies in a therapeutically compatible form using mRNA technology and lipid nanoparticles formulation'