PRIOR-M: Predicting treatment Response In spOndyloarthRitis using gut Microbiome
Supported project of Dirk Elewaut and Emilie Dumas : The gut-joint axis is a key concept in our current understanding of spondyloarthritis. Considering the emerging role of gut dysbiosis in its pathogenesis, this project will investigate the predictive value of gut microbial alterations and gut barrier integrity markers for assessment of treatment outcomes in axial SpA patients (i.e. responders versus non-responders). Microbiome-based predictive tools will allow informed clinical decision-making and pave the way towards personalized medicine.
Have also benefited from support
KU Leuven (RA Clinical Research Group, Skeletal Biology and Engineering Research Centre, Department of Development and Regeneration, KU Leuven)
What is the optimal tapering strategy for rituximab in patients with Rheumatoid Arthritis: comparison of interval prolongation with disease activity guided dose reduction
Supported project of Patrick Verschueren : Rituximab is an effective drug, but it is expensive and might be accompanied by an increased infection risk. Therefore, lowering the do…
Université Catholique de Louvain
Transcriptome study of individual cells isolated from synovial biopsies: can it help in the therapeutic management of early rheumatoid arthritis ?
Supported project of Patrick Durez : Early diagnosis and therapeutic management of Rheumatoid arthritis (RA) are crucial. Early RA is treated with methotrexate (MTX) and after 3 …
UZ Leuven/ KU Leuven
Clinical field tests as predictors of cardiorespiratory fitness and cardiometabolic risk in Psoriatic Arthritis.
Supported project of Barbara Neerinckx : This project will study the potential of low cost, objective and highly generalisable clinical field tests, six minute walk and hand grip…