This project aims to unravel which cells and molecules lie at the base of developing erosions and what differences exist between erosive and non-erosive osteoarthritis (OA). To this end, this project will elucidate the role of RANKL and the crosstalk between synovial fibroblasts and myeloid cells in erosive hand OA.
Support to the research project: 'Single Cell Technologies Applied To Healthy Articular Cartilage Profiling'
Supported project: SPIDER: Spondyloarthritis Precursors In first DEgree Relatives. Identifying gut microbiome alterations and early signs of subclinical gut inflammation in famil…